Nakafuku Lab

Ueki Y, Wilken MS, Cox KE, Chipman L, Jorstad N, Sternhagen K, Simic M, Ullom K, Nakafuku M, Reh TA. Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13717-22. 

Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL. In Vivo Reprogramming for Brain and Spinal Cord Repair. eNeuro. 2015 Nov 9;2(5). pii: ENEURO.0106-15.2015.

Andersen J, Urbán N, Achimastou A, Ito A, Simic M, Ullom K, Martynoga B, Lebel M, Göritz C, Frisén J, Nakafuku M, Guillemot F. A transcriptional mechanism integrating inputs from extracellular signals to activate hippocampal stem cells. Neuron. 2014 Sep 3;83(5):1085-97.

Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR. The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. J Neurosci. 2014 Mar 5;34(10):3767-78.

Grande A, Sumiyoshi K, López-Juárez A, Howard J, Sakthivel B, Aronow B, Campbell K, Nakafuku M. Environmental impact on direct neuronal reprogramming in vivo in the adult brain. Nat Commun. 2013;4:2373.

Nakafuku M, Grande A. Neurogenesis in the Damaged Mammalian Brain. In: Patterning and Cell Type Specification in the Developing CNS and PNS. Comprehensive Developmental Neuroscience Volume 1, Academic Press-Elsevier Inc. Maryland Heights, MO (2013).

Nakatani H, Martin E, Hassani H, Clavairoly A, Maire CL, Viadieu A, Kerninon C, Delmasure A, Frah M, Weber M, Nakafuku M, Zalc B, Thomas JL, Guillemot F, Nait-Oumesmar B, Parras C. Ascl1/Mash1 promotes brain oligodendrogenesis during myelination and remyelination.J Neurosci. 2013 Jun 5;33(23):9752-68.

López-Juárez A, Howard J, Ullom K, Howard L, Grande A, Pardo A, Waclaw R, Sun YY, Yang D, Kuan CY, Campbell K, Nakafuku M. Gsx2 controls region-specific activation of neural stem cells and injury-induced neurogenesis in the adult subventricular zone. Genes Dev. 2013 Jun 1;27(11):1272-87.

Chapman H, Waclaw RR, Pei Z, Nakafuku M, Campbell K. The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors. Development. 2013 Jun;140(11):2289-98.

Lee N, Batt MK, Cronier BA, Jackson MC, Bruno Garza JL, Trinh DS, Mason CO, Spearry RP, Bhattacharya S, Robitz R, Nakafuku M, MacLennan AJ. Ciliary neurotrophic factor receptor regulation of adult forebrain neurogenesis. J Neurosci. 2013 Jan 16;33(3):1241-58.

Nakafuku M, Grande. A. Neurogenesis in the Damaged Mammalian Brain. Patterning and Cell Type Specification in the Developing CNS and PNS - Comprehensive Developmental Neuroscience Volume 1. Academic Press-Elsevier Inc, Maryland Heights, MO. 2013.

Sugimori M, Nagao M, Bertrand N, Parras CM, Guillemot F, Nakafuku M. Combinatorial actions of patterning and HLH transcription factors in spatio-temporal control of neurogenesis and gliogenesis in the developing spinal cord. Development. 2007 Apr;134(8):1617-29.

Parras CM, Hunt C, Sugimori M, Nakafuku M, Rowitch D, Guillemot F. The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J. Neurosci. 2007 Apr 18;27(16):4233-42.a

Nagao M, Sugimori M, Nakafuku M. Cross talk between Notch and growth factor/cytokine signaling pathways in neural stem cells. Mol. Cell. Biol. 2007 27, 3982-3994.

Nakafuku M, Nagao M, Grande A, Cancelliere A. Revisiting neural stem cell identity. Proc. Natl. Acad. Sci. USA. 2008 Jan 22;105(3):829-30.

Sugimori M, Nagao M, Parras CM, Nakatani H, Lebel M, Guillemot F, Nakafuku M. Ascl1 is required for oligodendrocyte development in the spinal cord. Development. 2008 135, 1271-1281.

Nagao M, Campbell K, Burns K, Kuan C-Y, Trumpp A, Nakafuku M. Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway. J. Cell Biol. 2008 183, 1243-1257.

Zhong J, Kim H-T, Lyu J, Yoshikawa K, Nakafuku M., Lu W. The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development. Development. 2011 Feb;138(3):409-19.

Shereen A, Nemkul N, Yang D, Adhami F, Dunn RS, Hazen ML, Nakafuku M, Ning G, Lindquist DM, Kuan CY. Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke. J Cereb Blood Flow Metab. 2011 Apr;31(4):1155-69.

Pei Z, Wang B, Chen G, Nagao M, Nakafuku M, Campbell K. Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation. Proc. Natl. Acad. Sci. USA. 2011 Jan 25;108(4):1675-80.